Bovine Secondary Antibodies
Cayman Chemical ANTIBODY Mometason 500ug
A synthetic glucocorticoid; reduces pulmonary edema and neutrophil infiltration in a mouse model of chlorine-induced chemical lung injury at 3 mg/kg; intranasal administration reduces nose-rubbing behavior, sneezing, and nasal mucosal levels of IL-4 in a mouse model of allergic rhinitis at 0.2 UG/animal; reduces nasal mucosal epithelial destruction, fibrosis, and cilia loss in a rat model of oxymetazoline-induced rhinitis medicamentosa
Sino Biological Anti-VZV-gE (Research Grade Clone 4A2) 500 µg
This product is a recombinant monoclonal antibody expressed from HEK293 cells.
Cayman Chemical ANTIBODY SetosusIn 500ug
A fungal metabolite; reduces Aβ aggregate-induced neurotoxicity in PC12 cells (EC50 = 112.6 μM); induces tremors in mice at 30 mg/kg
Cayman Chemical ANTIBODY SM-164 500ug
A cell-permeable Smac mimetic and an inhibitor of XIAP; binds to BIR2 and BIR3 domain-containing XIAP (IC50 = 1.39 nM); inhibits growth (IC50 = 1 nM), as well as activates caspase-3 and caspase-9, and induces cleavage of PARP in HL-60 leukemia cells at 10 nM; reduces tumor volume by 80% in a 2LMP breast cancer mouse xenograft model at 5 mg/kg in combination with TRAIL
Cayman Chemical 13 S-HODE-bIotIn 500ug
13(S)-HODE is the LO metabolite of linoleic acid. 13(S)-HODE modulates the PAF, LTB4, and fMLP-induced calcium influx in human PMNL. The mechanism by which 13(S)-HODE elicits its inhibitory effect is still unclear. The use of biotinylated 15(S)-HETE as a probe for detecting binding proteins and/or receptors that specifically bind 15(S)-HETE provides a basis for similar use of 13(S)-HODE-biotin.
Cayman Chemical ANTIBODY BKT 140 500ug
A CXCR4 antagonist (IC50 = 0.91 nM); inhibits HIV-1-induced cytopathogenicity in MT-4 cells (EC50 = 4 nM); reduces CXCL12-induced migration of SUP-T1 leukemia and MDA-MB-231 at 100 nM; induces apoptosis in NB4 leukemia and RPMI-8226 multiple myeloma cancer cells at 8 and 40 µM; reduces pulmonary metastasis in an MDA-MB-231 mouse xenograft model; reduces the incidence of arthritis in a mouse model of collagen-induced arthritis
Cayman Chemical ANTIBODY RadIcIcol 500ug
An inhibitor of Hsp90 (IC50 = erb82, and mutant p53; binds to and inhibits DNA topoisomerase type II proteins and GRP94
Cayman Chemical ANTIBODY Dth 500ug
A PROTAC that drives aptamer-defined protein degradation; composed of DFHBI and thalidomide; induces degradation of mCherry in HEK293T cells at 20 µM; induces degradation of p50, as well as p50 and E2F1, in MCF-7 cells at 20 µM
Cayman Chemical ANTIBODY UrodIlatIn 500ug
A renal natriuretic peptide that regulates sodium and water reabsorption in the kidney; has pharmacological effects on renal, cardiovascular, and pulmonary parameters in animals
Cayman Chemical ANTIBODY VER-50589 500ug
An isoxazole compound that inhibits Hsp90 with an IC50 value of 21 nM; produces a mean cellular antiproliferative GI50 value of 78 nM when tested against a human cancer cell line panel
Cayman Chemical ANTIBODY U-51605 500ug
A stable analog of PGH2 that inhibits both PGI and TX synthases with more selectivity towards PGI synthase; a partial agonist at TP receptors
Cayman Chemical CoelenterazIn h 500ug
A synthetic derivative of native coelenterazine that exhibits 16-fold higher luminescence intensity (emission maximum ~466 nm; half-total time of 0.6-1.2 sec) than native coelenterazine
Cayman Chemical ANTIBODY CZC-8004 500ug
An aminopyrimidine that binds a range of tyrosine kinases, including ABL, BTK, FAK, FER, JAK1, SRC, SYK, TEC, TNK1, TYK2, and YES
Sino Biological Anti-NPR1 (Research Grade Clone REGN9035) 5 mg
This product is a recombinant monoclonal antibody expressed from CHO cells.